The Los Angeles Chargers will host their first game at Sofi Stadium against the defending Super Bowl Champions Kansas City Chiefs at 1:25 PT.
This will be their first matchup of the season until late December. Patrick Mahomes is 3-1 against the Chargers but has struggled against the Chargers defense in the past, and will be another key factor to keep an eye on in this game.

How the Offense Adjusts After a Rusty Last Week’s Performance
Last week was the first time any NFL stepped on the field for real competition, and it showed for a lot of teams that implemented new offenses or had new quarterbacks at the helm.
The Chargers had both, and the offense struggled to get the wheels rolling throughout the game but were fortunate enough to win due to the solid defensive play. The Charger offense will need to make adjustments against the defense of the Chiefs. The Chargers run game will be a key factor in this game, Justin Jackson is doubtful to play, so the Chargers have added both Darius Bradwell and Troymaine Pope to the active roster from the practice squad.
Austin Ekeler and Joshua Kelley will be the key to the Chargers winning the game this week.
Ekeler received a career-high in carries last week with 19, but only 1 target out of the backfield where he is most effective. A solid rushing attack helps the Chargers set up their play-action attack, which is where Tyrod Taylor is most effective. There will be some additional changes made to the offensive line this week, with Pro-Bowler Mike Pouncey opting for season-ending surgery on his hip and was placed on the IR.
Dan Feeney will be the starting center for the remainder of the season, and Forrest Lamp appears to have the starting left guard position after his impressive performance last week. Right guard Trai Turner will make his Chargers debut against the Chiefs and should add to the Chargers rushing attack.
Both Mike Williams and Hunter Henry were focal points of the offense in the win against the Bengals last week and with both healthy, they should be well utilized against the chiefs weakened secondary.
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